CrkL antibody [5E12]

Cannot supply to this region.

SKU:: GTX60462
Additional Names:: CRK like proto-oncogene, adaptor protein
Application:: ELISA, Flow Cytometry, WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human CRKL expressed in E. Coli.
Clone:: 5E12
Uniprot:: P46109
Synonyms:: crk-like protein;v-crk avian sarcoma virus CT10 oncogene homolog-like
Extra Details:: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]