GTX60359
MBD1 antibody - ChIP grade
Cannot supply to this region.
- SKU:
- GTX60359
- Additional Names:
- methyl-CpG binding domain protein 1 , CXXC3 , PCM1 , RFT
- Application:
- ChIP, ELISA, WB
- Concentration:
- 0.7 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.05% Sodium azide, 0.05% ProClin 300.
- Immunogen:
- Human MBD1 (Methyl-CpG-binding domain protein 1), using a KLH-conjugated synthetic peptide containing a sequence from the N-terminal part of the protein.
- Uniprot:
- Q9UIS9
- Synonyms:
- CXXC-type zinc finger protein 3;CXXC3;methyl-CpG-binding domain protein 1;Methyl-CpG-binding protein MBD1;PCM1;protein containing methyl-CpG-binding domain 1;RFT;the regulator of fibroblast growth factor 2 (FGF-2) transcription
- Extra Details:
- The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
- Shipping Conditions:
- Blue Ice