![QPRT antibody [AT24C4]](https://www.genetex.com/upload/website/prouct_img/normal/GTX57665/GTX57665_20200204_IF_w_23061123_658.webp)
![QPRT antibody [AT24C4]](https://www.genetex.com/upload/website/prouct_img/normal/GTX57665/GTX57665_20200204_WB_w_23061123_868.webp)
GTX57665
QPRT antibody [AT24C4]
Cannot supply to this region.
- SKU:
- GTX57665
- Additional Names:
- quinolinate phosphoribosyltransferase , HELS90n , QPRT , QPRTase
- Application:
- WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, 10% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The clone AT24C4 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human QPRT protein.
- Clone:
- AT24C4
- Uniprot:
- Q15274
- Synonyms:
- epididymis secretory sperm binding protein Li 90n;HEL-S-90n;nicotinate-nucleotide pyrophosphorylase (carboxylating);nicotinate-nucleotide pyrophosphorylase [carboxylating];QPRTase;Quinolinate phosphoribosyltransferase [decarboxylating]
- Extra Details:
- This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Shipping Conditions:
- Blue Ice