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  2. Monoclonal

GTX57563

14-3-3 epsilon antibody [AT4F8]

Cannot supply to this region.

SKU:
GTX57563
Additional Names:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon , HEL2 , KCIP1 , MDCR , MDS , YWHAE , tyrosine 3monooxygenase/tryptophan 5monooxygenase activation protein epsilon , 14-3-3 epsilon , 1433E
Application:
WB, IF, ICC
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human, Mouse
Buffer:
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:
The clone AT4F8 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-5 epsiilon protein.
Clone:
AT4F8
Uniprot:
P62258
Synonyms:
14-3-3 epsilon;14-3-3 protein epsilon;14-3-3E;epididymis luminal protein 2;HEL2;KCIP-1;MDCR;MDS;mitochondrial import stimulation factor L subunit;protein kinase C inhibitor protein-1;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide;tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide
Extra Details:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
Shipping Conditions:
Blue Ice