Bid antibody [4D3]

Cannot supply to this region.

SKU:: GTX57542
Additional Names:: BH3 interacting domain death agonist , BID , FP497 , Bid
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: The clone 4D3 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BID protein.
Clone:: 4D3
Uniprot:: P55957
Synonyms:: apoptic death agonist;BH3-interacting domain death agonist;desmocollin type 4;FP497;Human BID coding sequence;p22 BID
Extra Details:: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]