GTX57354-PRO
Human BCDIN3D protein, His tag
Cannot supply to this region.
- SKU:
- GTX57354-PRO
- Additional Names:
- BCDIN3 domain containing RNA methyltransferase
- Concentration:
- 0.25 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 200mM NaCl, 40% Glycerol, 1mM DTT, 2mM EDTA, no preservatives.
- Immunogen:
- BCDIN3 domain containing RNA methyltransferase
- Species:
- Human
- Uniprot:
- Q7Z5W3
- Synonyms:
- BCDIN3 domain containing RNA methyltransfease;BCDIN3 domain-containing protein;pre-miRNA 5'-monophosphate methyltransferase;probable methyltransferase BCDIN3D;RNA 5'-monophosphate methyltransferase
- Extra Details:
- This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
- Shipping Conditions:
- Dry Ice