MLH1 antibody [IHC409]

Cannot supply to this region.

SKU:: GTX57187
Additional Names:: Mutl Homolog 1 , Coca2 , Fcc2 , Hnpcc , Hnpcc2 , Hmlh1 , Mlh1
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tris, 1% BSA, 0.09% Sodium azide.
Immunogen:: Recombinant Human MLH1 protein.
Clone:: IHC409
Synonyms:: COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2
Extra Details:: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]