COL4A1 antibody [IHC549]

Cannot supply to this region.

SKU:: GTX57183
Additional Names:: Collagen Type Iv Alpha 1 Chain , Bsvd , Rator , Col4A1
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tris, 1% BSA, 0.09% Sodium azide.
Immunogen:: Human Placenta protein.
Clone:: IHC549
Synonyms:: arresten;BSVD;BSVD1;COL4A1 NC1 domain;COL4A1s;collagen alpha-1(IV) chain;collagen IV, alpha-1 polypeptide;collagen of basement membrane, alpha-1 chain;PADMAL;RATOR
Extra Details:: This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Shipping Conditions:: Blue Ice