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  2. Monoclonal

GTX57174

E-Cadherin antibody [IHC564]

Cannot supply to this region.

SKU:
GTX57174
Additional Names:
Cadherin 1 , Arc-1 , Bcds1 , Cd324 , Cdhe , Ecad , Lcam , Uvo , Cdh1
Application:
IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
Tris, 1% BSA, 0.09% Sodium azide.
Immunogen:
Recombinant Human E-cadherin protein.
Clone:
IHC564
Synonyms:
Arc-1;BCDS1;cadherin 1, E-cadherin (epithelial);cadherin 1, type 1, E-cadherin (epithelial);cadherin-1;calcium-dependent adhesion protein, epithelial;CAM 120/80;CD324;CDHE;cell-CAM 120/80;E-cadherin 1;ECAD;epididymis secretory sperm binding protein;epithelial cadherin;LCAM;UVO;uvomorulin
Extra Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice