GTX56290
CYP2E1 antibody
Cannot supply to this region.
- SKU:
- GTX56290
- Additional Names:
- cytochrome P450 family 2 subfamily E member 1 , CPE1 , CYP2E , P450-J , P450C2E
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of CYP2E1. The exact sequence is proprietary.
- Uniprot:
- P05181
- Synonyms:
- 4-nitrophenol 2-hydroxylase;CPE1;CYP2E;CYPIIE1;cytochrome P450 2E1;cytochrome P450-J;cytochrome P450, family 2, subfamily E, polypeptide 1;cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1;flavoprotein-linked monooxygenase;microsomal monooxygenase;P450-J;P450C2E;xenobiotic monooxygenase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice