GANP antibody

Cannot supply to this region.

SKU:: GTX55906
Additional Names:: minichromosome maintenance complex component 3 associated protein , GANP , MAP80 , PNRIID , SAC3
Application:: WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of GANP. The exact sequence is proprietary.
Uniprot:: O60318
Synonyms:: 80 kDa MCM3-associated protein;GANP;germinal center-associated nuclear protein;germinal-center associated nuclear protein;germinal-centre associated nuclear protein;MAP80;MCM3 acetylating protein;MCM3 acetyltransferase;MCM3 import protein;MCM3 minichromosome maintenance deficient 3 associated protein;PNRIID;SAC3
Extra Details:: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]

Shipping Conditions:: Blue Ice