Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Polyclonal

GTX55822

Tropomyosin 1 antibody

Cannot supply to this region.

SKU:
GTX55822
Additional Names:
tropomyosin 1 , C15orf13 , CMD1Y , CMH3 , HEL-S-265 , HTM-alpha , LVNC9 , TMSA
Application:
WB, IHC-P, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPM1 (NP_001018008.1).
Uniprot:
P09493
Synonyms:
Alpha-tropomyosin;C15orf13;cardiomyopathy, hypertrophic 3;CMD1Y;CMH3;epididymis secretory protein Li 265;HEL-S-265;HTM-alpha;LVNC9;sarcomeric tropomyosin kappa;TMSA;tropomyosin alpha-1 chain;Tropomyosin-1
Extra Details:
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice