GTX55783
RNF8 antibody
Cannot supply to this region.
- SKU:
- GTX55783
- Additional Names:
- ring finger protein 8 , hRNF8
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNF8 (NP_003949.1).
- Uniprot:
- O76064
- Synonyms:
- C3HC4-type zinc finger protein;E3 ubiquitin-protein ligase RNF8;hRNF8;ring finger protein (C3HC4 type) 8;RING finger protein 8;ring finger protein 8, E3 ubiquitin protein ligase;RING-type E3 ubiquitin transferase RNF8;UBC13/UEV-interacting ring finger protein
- Extra Details:
- The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- Shipping Conditions:
- Blue Ice