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  2. Polyclonal

GTX55702

MEK5 antibody

Cannot supply to this region.

SKU:
GTX55702
Additional Names:
mitogen-activated protein kinase kinase 5 , HsT17454 , MAPKK5 , MEK5 , PRKMK5
Application:
WB, IHC-P, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MAP2K5 (NP_660143.1).
Uniprot:
Q13163
Synonyms:
dual specificity mitogen-activated protein kinase kinase 5;HsT17454;MAP kinase kinase 5;MAP kinase kinase MEK5b;MAPK/ERK kinase 5;MAPKK 5;MAPKK5;MEK 5;MEK5;PRKMK5
Extra Details:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
Shipping Conditions:
Blue Ice