Coilin antibody

Cannot supply to this region.

SKU:: GTX55575
Additional Names:: coilin , CLN80 , p80-coilin
Application:: WB, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human COIL (NP_004636.1).
Uniprot:: P38432
Synonyms:: CLN80;coilin;coilin p80;p80;p80-coilin
Extra Details:: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]