GTX55451
WAVE1 (phospho Tyr125) antibody
Cannot supply to this region.
- SKU:
- GTX55451
- Additional Names:
- WASP family member 1 , SCAR1 , WAVE , WAVE1
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 125 (E-T-Y(p)-D-V) derived from human WAVE1.
- Uniprot:
- Q92558
- Synonyms:
- homology of dictyostelium scar 1;NEDALVS;protein WAVE-1;SCAR1;verprolin homology domain-containing protein 1;WAS protein family member 1;WASP family protein member 1;WAVE;WAVE1;wiskott-Aldrich syndrome protein family member 1
- Extra Details:
- The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice