GTX55310
ACK1 (phospho Tyr284) antibody
Cannot supply to this region.
- SKU:
- GTX55310
- Additional Names:
- tyrosine kinase non receptor 2 , ACK , ACK-1 , ACK1 , p21cdc42Hs
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 284 (D-H-Y(p)-V-M) derived from human ACK1.
- Uniprot:
- Q07912
- Synonyms:
- ACK;ACK-1;ACK1;activated CDC42 kinase 1;activated Cdc42-associated kinase 1;activated p21cdc42Hs kinase;p21cdc42Hs;tyrosine kinase non-receptor protein 2
- Extra Details:
- This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice