GTX55159
MLCK antibody
Cannot supply to this region.
- SKU:
- GTX55159
- Additional Names:
- myosin light chain kinase , AAT7 , KRP , MLCK , MLCK1 , MLCK108 , MLCK210 , MSTP083 , MYLK1 , smMLCK
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of MLCK. The exact sequence is proprietary.
- Uniprot:
- Q15746
- Synonyms:
- AAT7;kinase-related protein;KRP;MLCK;MLCK1;MLCK108;MLCK210;MMIHS;MMIHS1;MSTP083;MYLK1;myosin light chain kinase, smooth muscle;myosin, light polypeptide kinase;smMLCK;smooth muscle myosin light chain kinase;telokin
- Extra Details:
- This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice