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Nav1.2 antibody

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  2. Polyclonal

GTX54797

Nav1.2 antibody

Cannot supply to this region.

SKU:
GTX54797
Additional Names:
sodium voltage-gated channel alpha subunit 2 , NachII , Nav1.2 , RII/RIIA , RNSCPIIR , SCN , Scn2a1 , Scn2a2 , ScpII
Application:
WB, IHC-Fr, IF, ICC, IP
Concentration:
0.8 mg/ml
Physical State:
Liquid
Species Reactivity:
Human, Rat
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 1% BSA, 0.05% Sodium azide.
Immunogen:
Peptide (C)ASAESRDFSGAGGIGVFSE, corresponding to amino acid residues 467-485 (Intracellular loop between domains I and II) of rat NaV1.2 (Accession : P04775).
Uniprot:
P04775
Synonyms:
NachII;Nav1.2;RII/RIIA;RIIA sodium channel protein;RNSCPIIR;SCN;Scn2a1;Scn2a2;ScpII;Sodium channel protein brain II subunit alpha;sodium channel protein type 2 subunit alpha;sodium channel protein type II subunit alpha;sodium channel protein, brain II subunit alpha;sodium channel voltage-gated type II alpha polypeptide;sodium channel, voltage-gated, type 2, alpha 1 polypeptide;sodium channel, voltage-gated, type 2, alpha 1 subunit;sodium channel, voltage-gated, type II, alpha 1;sodium channel, voltage-gated, type II, alpha subunit;voltage-gated sodium channel subunit alpha Nav1.2
Extra Details:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. [provided by RefSeq, Nov 2016]
Shipping Conditions:
Blue Ice