Dectin-2 antibody

Cannot supply to this region.

SKU:: GTX54664
Additional Names:: C-type lectin domain containing 6A , CLEC4N , CLECSF10 , dectin-2
Application:: Flow Cytometry, IHC, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Serum, no preservatives.
Immunogen:: Human Dectin-2.
Uniprot:: Q6EIG7
Synonyms:: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10;C-type lectin domain family 6 member A;C-type lectin superfamily member 10;CLEC4N;CLECSF10;DC-associated C-type lectin 2;dectin 2;dectin-2;dendritic cell-associated C-type lectin 2;hDECTIN-2
Extra Details:: The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]