COL17A1 antibody [NC16a-3]

Cannot supply to this region.

SKU:: GTX54647
Additional Names:: collagen type XVII alpha 1 chain , BA16H23.2 , BP180 , BPA-2 , BPAG2 , ERED , LAD-1
Application:: ELISA, WB, IHC-P, IHC-Fr
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Purified recombinant NC16a-domain of collagen XVII. The epitope has been mapped to aa545-557 (PMID: 19158842).
Clone:: NC16a-3
Uniprot:: Q9UMD9
Synonyms:: 180 kDa bullous pemphigoid antigen 2;alpha 1 type XVII collagen;BA16H23.2;bA16H23.2 (collagen, type XVII, alpha 1 (BP180));BP180;BPA-2;BPAG2;Bullous pemphigoid antigen 2;bullous pemphigoid antigen 2 (180kD);collagen alpha-1(XVII) chain;collagen XVII, alpha-1 polypeptide;collagen, type XVII, alpha 1;ERED;LAD-1;type XVII collagen alpha-1
Extra Details:: This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice