GTX54604
PDZK1 antibody
Cannot supply to this region.
- SKU:
- GTX54604
- Additional Names:
- PDZ domain containing 1 , CAP70 , CLAMP , NHERF-3 , NHERF3 , PDZD1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDZK1 (NP_001188254.1).
- Uniprot:
- Q5T2W1
- Synonyms:
- CAP70;CFTR-associated protein of 70 kDa;CLAMP;Na(+)/H(+) exchange regulatory cofactor NHE-RF3;Na(+)/H(+) exchanger regulatory factor 3;na/Pi cotransporter C-terminal-associated protein 1;naPi-Cap1;NHERF-3;NHERF3;PDZ domain-containing protein 1;PDZ-containing kidney protein 1;PDZD1;sodium-hydrogen exchanger regulatory factor 3
- Extra Details:
- This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- Shipping Conditions:
- Blue Ice