GTX54529
Src (phospho Tyr416) antibody (Alexa Fluor 488)
Cannot supply to this region.
- SKU:
- GTX54529
- Additional Names:
- SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Purification:
- Purified
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light., -20[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Canine, Human, Mouse
- Buffer:
- PBS, 0.02% BSA, 0.05% Sodium azide.
- Immunogen:
- This antibody was produced against a chemically synthesized phosphopeptide derived from the region of Src that contains tyrosine 416. The antibody was affinity purified by sequential epitope-specific chromatography, then conjugated to Alexa Fluor 488. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.
- Uniprot:
- P12931
- Synonyms:
- ASV;c-SRC;p60-Src;pp60c-src;proto-oncogene c-Src;proto-oncogene tyrosine-protein kinase Src;protooncogene SRC, Rous sarcoma;SRC1;THC6;tyrosine kinase pp60c-src;tyrosine-protein kinase SRC-1;v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
- Extra Details:
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice