GTX54518
Vinculin (phospho Tyr1065) antibody
Cannot supply to this region.
- SKU:
- GTX54518
- Additional Names:
- vinculin , CMD1W , CMH15 , HEL114 , MV , MVCL
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.1% BSA, 50% Glycerol, 0.05% Sodium azide.
- Immunogen:
- The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human vinculin that contains tyrosine 1065. The sequence is conserved in mouse and chicken.
- Uniprot:
- P18206
- Synonyms:
- CMD1W;CMH15;epididymis luminal protein 114;epididymis secretory sperm binding protein;HEL114;meta-vinculin;metavinculin;MV;MVCL;vinculin;vinculin isoform meta-VCL
- Extra Details:
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice