GTX54377
MSH2 antibody
Cannot supply to this region.
- SKU:
- GTX54377
- Additional Names:
- mutS homolog 2 , COCA1 , FCC1 , HNPCC , HNPCC1 , LCFS2 , hMSH2
- Application:
- WB, IP
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1).
- Uniprot:
- P43246
- Synonyms:
- COCA1;DNA mismatch repair protein Msh2;DNA mismatch repair protein Msh2 transcript;FCC1;hMSH2;HNPCC;HNPCC1;LCFS2;MMRCS2;mutS homolog 2, colon cancer, nonpolyposis type 1;MutS protein homolog 2
- Extra Details:
- This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
- Shipping Conditions:
- Blue Ice