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  2. Polyclonal

GTX54352

MEK7 antibody

Cannot supply to this region.

SKU:
GTX54352
Additional Names:
mitogen-activated protein kinase kinase 7 , JNKK2 , MAPKK7 , MEK , MEK 7 , MKK7 , PRKMK7 , SAPKK-4 , SAPKK4
Application:
WB, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MAP2K7 (NP_660186.1).
Uniprot:
O14733
Synonyms:
c-Jun N-terminal kinase kinase 2;dual specificity mitogen-activated protein kinase kinase 7;JNK-activating kinase 2;JNKK2;MAP kinase kinase 7;MAPK/ERK kinase 7;MAPKK7;MEK;MEK 7;MKK7;PRKMK7;SAPK kinase 4;SAPKK-4;SAPKK4;stress-activated protein kinase kinase 4
Extra Details:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Shipping Conditions:
Blue Ice