GTX54343
JNK3 antibody
Cannot supply to this region.
- SKU:
- GTX54343
- Additional Names:
- mitogen-activated protein kinase 10 , JNK3 , JNK3A , PRKM10 , SAPK1b , p493F12 , p54bSAPK
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 175-464 of human MAPK10 (NP_620448.1).
- Uniprot:
- P53779
- Synonyms:
- c-Jun N-terminal kinase 3;JNK3;JNK3 alpha protein kinase;JNK3A;MAP kinase 10;MAP kinase p49 3F12;mitogen-activated protein kinase 10;p493F12;p54bSAPK;PRKM10;SAPK1b;stress activated protein kinase beta;stress-activated protein kinase 1b;stress-activated protein kinase JNK3
- Extra Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
- Shipping Conditions:
- Blue Ice