IDO1 antibody [10.1]

Cannot supply to this region.

SKU:: GTX54075
Additional Names:: indoleamine 2,3-dioxygenase 1 , IDO , IDO-1 , INDO
Application:: WB, IHC-Fr
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, 0.1% Sodium azide.
Immunogen:: Peptide corresponding to amino acids 78-184 of human IDO fused to GST.
Clone:: 10.1
Uniprot:: P14902
Synonyms:: IDO;IDO-1;INDO;indolamine 2,3 dioxygenase;indole 2,3-dioxygenase;indoleamine 2,3-dioxygenase 1;indoleamine-pyrrole 2,3-dioxygenase
Extra Details:: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]

Shipping Conditions:: Blue Ice