CD11b antibody [OX-42] (Biotin)

Cannot supply to this region.

SKU:: GTX53827
Additional Names:: Integrin Subunit Alpha M , Cd11B , Itgam
Application:: Flow Cytometry, IHC, IHC-Fr
Concentration:: 0.1 mg/ml
Physical State:: Liquid
Species Reactivity:: Rat
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Rat
Buffer:: PBS, BSA, 0.02% Sodium azide.
Immunogen:: Rat peritoneal macrophages
Clone:: OX-42
Synonyms:: Cd11b;integrin alpha-M;integrin, alpha M
Extra Details:: CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes and is commonly used as a microglial marker in nervous tissue.GTX53827 recognises CD11b expressed on most macrophages, including resident and activated peritoneal macrophages, Kupffer cells, around 35% of alveolar macrophages, dendritic cells, granulocytes and microglial cells in the brain.

Shipping Conditions:: Blue Ice