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  2. Monoclonal

GTX53760

PDZK1 antibody [AT1A2]

Cannot supply to this region.

SKU:
GTX53760
Additional Names:
PDZ domain containing 1 , CAP70 , CLAMP , NHERF-3 , NHERF3 , PDZD1
Application:
ELISA, WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant human PDZK1 (1-519aa) purified from E. coli
Clone:
AT1A2
Uniprot:
Q5T2W1
Synonyms:
CAP70;CFTR-associated protein of 70 kDa;CLAMP;Na(+)/H(+) exchange regulatory cofactor NHE-RF3;Na(+)/H(+) exchanger regulatory factor 3;na/Pi cotransporter C-terminal-associated protein 1;naPi-Cap1;NHERF-3;NHERF3;PDZ domain-containing protein 1;PDZ-containing kidney protein 1;PDZD1;sodium-hydrogen exchanger regulatory factor 3
Extra Details:
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Shipping Conditions:
Blue Ice