MyD88 antibody [AT22F11]

Cannot supply to this region.

SKU:: GTX53746
Additional Names:: MYD88 innate immune signal transduction adaptor , MYD88D
Application:: ELISA, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant human MYD88 (1-309aa) purified from E. coli
Clone:: AT22F11
Uniprot:: Q99836
Synonyms:: IMD68;mutant myeloid differentiation primary response 88;MYD88D;myeloid differentiation primary response 88;myeloid differentiation primary response gene (88);myeloid differentiation primary response protein MyD88
Extra Details:: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Shipping Conditions:: Blue Ice