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  2. Monoclonal

GTX53738

MAFK antibody [AT2F7]

Cannot supply to this region.

SKU:
GTX53738
Additional Names:
MAF bZIP transcription factor K , NFE2U , P18
Application:
ELISA, WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant human MAFK (1-156aa) purified from E. coli
Clone:
AT2F7
Uniprot:
O60675
Synonyms:
basic-leucine zipper transcription factor MafK;erythroid transcription factor NF-E2 p18 subunit;NFE2U;nuclear factor erythroid-2, ubiquitous (p18);P18;transcription factor MafK;v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K;v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
Extra Details:
The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]
Shipping Conditions:
Blue Ice