MIB1 antibody

Cannot supply to this region.

SKU:: GTX53672
Additional Names:: mindbomb E3 ubiquitin protein ligase 1 , DIP-1 , DIP1 , LVNC7 , MIB , ZZANK2 , ZZZ6
Application:: WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: SAS Precipitated; Dialysis
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human Mib1/Mindbomb.
Uniprot:: Q86YT6
Synonyms:: DAPK-interacting protein 1;DIP-1;DIP1;E3 ubiquitin-protein ligase MIB1;LVNC7;MIB;Mind bomb homolog 1;mindbomb E3 ubiquitin protein ligase 1;RING-type E3 ubiquitin transferase MIB1;ubiquitin ligase mind bomb;zinc finger ZZ type with ankyrin repeat domain protein 2;ZZANK2;ZZZ6
Extra Details:: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]