GTX53429
Granzyme B antibody [14G13]
Cannot supply to this region.
- SKU:
- GTX53429
- Application:
- WB
- Concentration:
- 500 ug/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Purification:
- protein a/g purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Mouse recombinant protein Granzyme B
- Clone:
- 14G13
- Uniprot:
- P04187
- Synonyms:
- AI553453;CCP;CCP-1/C1;CCP-1/C11;CCP1;Ctl;Ctla;Ctla-1;Ctla1;cytotoxic cell protease 1;fragmentin-2;granzyme B(G,H);GZB
- Extra Details:
- This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]
- Shipping Conditions:
- Blue Ice