GDF8 / Myostatin antibody [13F2]

Cannot supply to this region.

SKU:: GTX53334
Application:: WB
Concentration:: 500 ug/ml
Physical State:: Liquid
Species Reactivity:: Mouse
Purification:: protein a/g purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Mouse recombinant protein GDF-8
Clone:: 13F2
Uniprot:: O08689
Synonyms:: Cmpt;Gdf8;growth/differentiation factor 8;Myostatin
Extra Details:: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Homozygous knockout mice for this gene exhibit increased muscle mass and bone density, and reduced adiposity. [provided by RefSeq, Jul 2016]