Cathepsin B antibody [6C15]

Cannot supply to this region.

SKU:: GTX53252
Application:: WB
Concentration:: 500 ug/ml
Physical State:: Liquid
Species Reactivity:: Mouse
Purification:: protein a/g purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Mouse recombinant protein of Cathepsin B
Clone:: 6C15
Uniprot:: P10605
Synonyms:: cathepsin B;cathepsin B1;CB
Extra Details:: This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]