KIR2DS4 antibody [2G42]

Cannot supply to this region.

SKU:: GTX52897
Additional Names:: CD158I , KIR1D , KIR2DS1 , KIR2DS4 , KIR412 , KKA3 , NKAT8 , killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
Application:: Flow Cytometry, WB
Concentration:: 500 ug/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Human recombinant KIR2DS4
Clone:: 2G42
Uniprot:: P43632
Synonyms:: CD158 antigen-like family member I;CD158I;killer cell immunoglobulin-like receptor 2DS4;killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4;killer inhibitory receptor 4-1-2;KIR antigen 2DS4;KIR-2DS4;KIR1D;KIR412;KKA3;MHC class I NK cell receptor;natural killer-associated transcript 8;NKAT-8;NKAT8;p50 killer cell activating receptor KAR-K1d;P58 natural killer cell receptor clones CL-39/CL-17;p58 NK receptor CL-39/CL-17
Extra Details:: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice