GTX52868
Insulin Receptor beta antibody [2A12]
Cannot supply to this region.
- SKU:
- GTX52868
- Additional Names:
- CD220 , HHF5 , INSR , insulin receptor , Insulin Receptor
- Application:
- WB
- Concentration:
- 500 ug/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Human recombinant Insulin R EC domain
- Clone:
- 2A12
- Uniprot:
- P06213
- Synonyms:
- CD220;HHF5;insulin receptor;IR
- Extra Details:
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- Shipping Conditions:
- Blue Ice