IL18BP antibody [10G36]

Cannot supply to this region.

SKU:: GTX52833
Additional Names:: IL18BP , IL18BPa , interleukin 18 binding protein , IL18 binding protein
Application:: WB
Concentration:: 500 ug/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Human recombinant IL-18 BPa
Clone:: 10G36
Uniprot:: O95998
Synonyms:: FVH;IL18BPa;interleukin-18-binding protein;MC51L-53L-54L homolog gene product;tadekinig-alfa
Extra Details:: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]