Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Monoclonal

GTX52815

IL12 antibody [7M58]

Cannot supply to this region.

SKU:
GTX52815
Additional Names:
CLMF , IL12A , NFSK , NKSF1 , P35 , interleukin 12A , IL12 p35
Application:
WB, IHC-Fr, Neutralisation
Concentration:
500 ug/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein G Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, no preservatives.
Immunogen:
Human recombinant IL-12
Clone:
7M58
Uniprot:
P29459
Synonyms:
CLMF;CLMF p35;cytotoxic lymphocyte maturation factor 1, p35;cytotoxic lymphocyte maturation factor 35 kDa subunit;IL-12 subunit p35;IL-12, subunit p35;IL-12A;IL35 subunit;interleukin 12, p35;interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35);interleukin-12 alpha chain;interleukin-12 subunit alpha;NF cell stimulatory factor chain 1;NFSK;NK cell stimulatory factor chain 1;NKSF1;P35
Extra Details:
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice