GTX52766
GITR antibody [7R12]
Cannot supply to this region.
- SKU:
- GTX52766
- Additional Names:
- AITR , CD357 , GITR , GITRD , TNF receptor superfamily member 18 , TNFRSF18
- Application:
- Flow Cytometry, WB, Neutralisation
- Concentration:
- 500 ug/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Human recombinant TNFRSF18 EC domain
- Clone:
- 7R12
- Uniprot:
- Q9Y5U5
- Synonyms:
- activation-inducible TNFR family receptor;AITR;CD357;ENERGEN;GITR;GITR-D;glucocorticoid-induced TNFR-related protein;TNF receptor superfamily activation-inducible protein;tumor necrosis factor receptor superfamily member 18
- Extra Details:
- This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
- Shipping Conditions:
- Blue Ice