TGF beta Receptor 2 antibody [4F14]

Cannot supply to this region.

SKU:: GTX52507
Additional Names:: AAT3 , FAA3 , LDS1B , LDS2 , LDS2B , MFS2 , RIIC , TAAD2 , TGFBR2 , TGFR2 , TGFbetaRII , transforming growth factor beta receptor 2 , TGF beta Receptor 2 , TGF beta Receptor II , TGF-beta RII
Application:: WB, IHC-P
Concentration:: 200 ug/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant hu-TGFB BetaRII extra cellular domain
Clone:: 4F14
Uniprot:: P37173
Synonyms:: AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;tbetaR-II;TBR-ii;TBRII;TGF-beta receptor type IIB;TGF-beta receptor type-2;TGF-beta type II receptor;TGFbeta-RII;TGFR-2;transforming growth factor beta receptor II;transforming growth factor beta receptor type IIC;Transforming growth factor-beta receptor type II;transforming growth factor, beta receptor II (70/80kDa);transforming growth factor, beta receptor II alpha;transforming growth factor, beta receptor II beta;transforming growth factor, beta receptor II delta;transforming growth factor, beta receptor II epsilon;transforming growth factor, beta receptor II gamma
Extra Details:: The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]

Shipping Conditions:: Blue Ice