GTX51761
PDCD10 antibody
Cannot supply to this region.
- SKU:
- GTX51761
- Additional Names:
- programmed cell death 10 , CCM3 , TFAR15
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Rat
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- 1% BSA, 50% Glycerol, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide derived from human PDCD10.
- Uniprot:
- Q9BUL8
- Synonyms:
- apoptosis-related protein 15;CCM3;cerebral cavernous malformations 3 protein;programmed cell death protein 10;TF-1 cell apoptosis-related protein 15;TFAR15
- Extra Details:
- This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice