GTX50496
NMDAR2B antibody
Cannot supply to this region.
- SKU:
- GTX50496
- Additional Names:
- glutamate ionotropic receptor NMDA type subunit 2B , EIEE27 , GluN2B , MRD6 , NMDAR2B , NR2B , NR3 , hNR3
- Application:
- IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around aa.1472~1476 (H-V-Y-E-K) derived from human NMDAR2B.
- Uniprot:
- Q13224
- Synonyms:
- DEE27;EIEE27;GluN2B;GluN2B(alt_5'UTR);glutamate [NMDA] receptor subunit epsilon-2;glutamate receptor ionotropic, NMDA 2B;glutamate receptor subunit epsilon-2;glutamate receptor, ionotropic, N-methyl D-aspartate 2B;hNR3;MRD6;N-methyl D-aspartate receptor subtype 2B;N-methyl-D-aspartate receptor subunit 3;NMDAR2B;NR2B;NR3
- Extra Details:
- This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
- Shipping Conditions:
- Blue Ice