GTX50347
PLCG2 (phospho Tyr1217) antibody
Cannot supply to this region.
- SKU:
- GTX50347
- Additional Names:
- phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from human PLCG2.
- Uniprot:
- P16885
- Synonyms:
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2;APLAID;FCAS3;phosphoinositide phospholipase C-gamma-2;Phospholipase C-gamma-2;phospholipase C-IV;phospholipase C, gamma 2 (phosphatidylinositol-specific);PLC-gamma-2;PLC-IV
- Extra Details:
- The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
- Shipping Conditions:
- Blue Ice