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  2. Polyclonal

GTX50306

alpha Synuclein (phospho Tyr136) antibody

Cannot supply to this region.

SKU:
GTX50306
Additional Names:
synuclein alpha , NACP , PARK1 , PARK4 , PD1
Application:
WB, IF, ICC
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 136 (Q-D-Y(p)-E-P) derived from human alpha Synuclein.
Uniprot:
P37840
Synonyms:
alpha-synuclein;I+/--synuclein;NACP;non A-beta component of AD amyloid;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;PARK1;PARK4;PD1;synuclein alpha-140;synuclein, alpha (non A4 component of amyloid precursor);truncated alpha synuclein
Extra Details:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Shipping Conditions:
Blue Ice