RASSF1A antibody [3F3]

Cannot supply to this region.

SKU:: GTX50075
Additional Names:: Ras association domain family member 1 , 123F2 , NORE2A , RASSF1A , RDA32 , REH3P21
Application:: ELISA, WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.1% Sodium azide.
Immunogen:: Recombinant human RASSF1A (1-340aa) purified from E. coli
Clone:: 3F3
Uniprot:: Q9NS23
Synonyms:: 123F2;cardiac-specific ras association domain family 1 protein;NORE2A;pancreas-specific ras association domain family 1 protein;Ras association (RalGDS/AF-6) domain family member 1;ras association domain-containing protein 1;RASSF1A;RDA32;REH3P21;tumor suppressor protein RDA32;WUGSC:H_LUCA12.5
Extra Details:: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]

Shipping Conditions:: Blue Ice