![LITAF antibody [AT1F9]](https://www.genetex.com/upload/website/prouct_img/normal/GTX50019/LITAF-antibody-AT1F9_Western-blot_GTX50019-1_w_23060823_891.webp)
GTX50019
LITAF antibody [AT1F9]
Cannot supply to this region.
- SKU:
- GTX50019
- Additional Names:
- lipopolysaccharide induced TNF factor , PIG7 , SIMPLE , TP53I7
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Recombinant human LITAF (1-161aa) purified from E. coli
- Clone:
- AT1F9
- Uniprot:
- Q99732
- Synonyms:
- lipopolysaccharide-induced TNF-alpha factor;lipopolysaccharide-induced tumor necrosis factor-alpha factor;LPS-induced TNF-alpha factor;p53-induced gene 7 protein;PIG7;SIMPLE;small integral membrane protein of lysosome/late endosome;TP53I7;tumor protein p53 inducible protein 7
- Extra Details:
- Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
- Shipping Conditions:
- Blue Ice