TXNRD2 antibody [3F2-E12-F10]

Cannot supply to this region.

SKU:: GTX49270
Additional Names:: thioredoxin reductase 2 , GCCD5 , SELZ , TR , TR-BETA , TR3 , TRXR2
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.5% BSA, 50% glycerol, 0.02% Sodium azide.
Immunogen:: Purified recombinant human TXNRD2 protein fragments expressed in E.coli.
Clone:: 3F2-E12-F10
Uniprot:: Q9NNW7
Synonyms:: GCCD5;selenoprotein Z;SELZ;thioredoxin reductase 2, mitochondrial;thioredoxin reductase 3;thioredoxin reductase beta;thioredoxin reductase TR3;TR;TR-BETA;TR3;TRXR2
Extra Details:: The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene. [provided by RefSeq, Jun 2017]

Shipping Conditions:: Blue Ice