CRK antibody [3H7-E5-H8]

Cannot supply to this region.

SKU:: GTX49212
Additional Names:: CRK proto-oncogene, adaptor protein , CRKII , p38
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.5% BSA, 50% glycerol, 0.02% Sodium azide.
Immunogen:: Purified recombinant human CRK protein fragments expressed in E.coli.
Clone:: 3H7-E5-H8
Uniprot:: P46108
Synonyms:: adapter molecule crk;CRKII;p38;proto-oncogene c-Crk;v-crk avian sarcoma virus CT10 oncogene homolog;v-crk sarcoma virus CT10 oncogene-like protein
Extra Details:: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice